Description
Buy injectable L-carnitine for sale. Premium l carnitine injection and shots for weight loss. Find l carnitine near me with fast, reliable global supply. A naturally occurring quaternary ammonium compound derived from the amino acids lysine and methionine. It plays a critical role in cellular energy metabolism by transporting long-chain fatty acids into mitochondria for β-oxidation.
Buy Injectable L-Carnitine
- Chemical Name: (R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
- Form: Liquid Solution
- Pharmacological Category: Metabolic agent
- Mechanism: L-Carnitine functions as an essential cofactor in mitochondrial fatty-acid transport and cellular energy metabolism. Its mechanism is biochemical rather than receptor-mediated.
Primary Mechanism: Carnitine Shuttle System
L-Carnitine enables the transport of long-chain fatty acids (LCFAs) into the mitochondrial matrix for β-oxidation.
Step-by-Step Process:
1. Activation of Fatty Acids (Cytosol)
- Long-chain fatty acids are converted into fatty acyl-CoA by acyl-CoA synthetase.
- Fatty acyl-CoA cannot directly cross the inner mitochondrial membrane.
2. Formation of Acyl-Carnitine
- Carnitine palmitoyltransferase I (CPT-I), located on the outer mitochondrial membrane, transfers the acyl group from CoA to L-Carnitine.
- This forms acyl-carnitine.
3. Transport Across the Inner Membrane
-
Acyl-carnitine is transported into the mitochondrial matrix via carnitine–acylcarnitine translocase (CACT).
4. Regeneration of Acyl-CoA
- Inside the matrix, CPT-II converts acyl-carnitine back into acyl-CoA.
- Free L-Carnitine returns to the cytosol to repeat the cycle.
5. β-Oxidation
- Acyl-CoA undergoes β-oxidation.
- Produces acetyl-CoA → enters TCA cycle → ATP production.
Secondary Mechanisms
| Mechanism | Functional Outcome |
|---|---|
| Removal of excess acyl groups | Prevents toxic acyl-CoA accumulation |
| Modulation of CoA/Acetyl-CoA ratio | Supports metabolic flexibility |
| Reduction of oxidative stress (indirect) | Improves mitochondrial efficiency |
| Ammonia detox support | Assists in hepatic metabolic balance |
Physical Properties (Finished Liquid Product)
| Parameter | Typical Specification |
|---|---|
| Active Ingredient | L-Carnitine (Levocarnitine) |
| Concentration | 600 mg/mL |
| Total Content | 6000 mg per 10 mL |
| Appearance | Clear, colorless to slightly pale yellow solution |
| Odor | Mild characteristic |
| Taste | Slightly acidic to neutral (may be flavored) |
| pH | 5.0 – 7.0 |
| Solubility | Completely miscible with water |
| Density | ~1.05 – 1.15 g/mL (depends on excipients) |
| Viscosity | Slightly viscous (if syrup-based) |
| Packaging | Amber glass vial or plastic ampoule |
| Storage Sensitivity | Protect from light and excessive heat |
Chemical Assay & Quality Control (Finished Product)
| Test Parameter | Typical Specification | Analytical Method |
|---|---|---|
| Assay (L-Carnitine content) | 95.0% – 105.0% of label claim | HPLC |
| Identification | Positive | HPLC / IR |
| Related Substances (Impurities) | ≤ 1.0% total | HPLC |
| Microbial Limit Test | As per USP/EP limits | Plate Count Method |
| pH Verification | 5.0 – 7.0 | pH meter |
| Specific Gravity | Within manufacturer specification | Density meter |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Preservative Content (if added) | Within declared limits | HPLC |
| Appearance | Clear, no visible particles | Visual inspection |
Half-Life
- Plasma half-life: ~17 hours (varies with dose and renal function)
- Primarily excreted via kidneys
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