Buy 3,4-MDEA (hydrochloride) (CAS 74341-78-9)

Description

Buy MDEA Online

Looking to buy 3,4-Methylenedioxyethylamphetamine hydrochloride (commonly abbreviated as MDEA, MDE, and also known as “Eve”) China Chem Supplies offers high-purity MDEA powder price wholesale with fast delivery.

What is MDEA?

 It is a synthetic psychoactive compound belonging to the phenethylamine, amphetamine, and methylenedioxyphenethylamine chemical classes. MDEA is used recreationally in a similar manner to MDMA (also called ecstasy), however the subjective effects of MDEA are milder and shorter lasting.

Basic Chemical & Physical Identification

• Chemical Name (IUPAC): N-ethyl-1-(1,3-benzodioxol-5-yl)propan-2-amine hydrochloride

• CAS Registry Number: 74341-78-9 (hydrochloride salt); 82801-81-8 (free base)

• Molecular Formula: C12H17NO2 HCl

• Formula Weight: 243.73 g/mol

• Free Base Formula Weight: 207.27 g/mol

• InChIKey: IBDIPBWIXJRJQM-UHFFFAOYSA-N

• SMILES: CC(NCC)CC1=CC(OCO2)=C2C=C1.Cl

• Physical Appearance: Typically appears as a white to off-white crystalline solid or fine powder.

Structural Relationship & Chemistry

MDEA is a close structural analogue of MDMA (ecstasy) and MDA.

• It differs structurally from MDMA only at the nitrogen atom: MDMA has a methyl group (-CH3) attached to the nitrogen, whereas MDEA features an ethyl group (-CH2CH3).

• Its synthesis typically proceeds via the reductive amination of isosafrole or 3,4-methylenedioxyphenyl-2-propanone (MDP2P) using ethylamine.

Pharmacology & Mechanism of Action

• Primary Mechanism: MDEA acts primarily as a monoamine releasing agent and reuptake inhibitor. It elevates synaptic levels of serotonin (5-HT), norepinephrine (NE), and dopamine (DA).

• Classification: Classified as an empathogen-entactogen and mild central nervous system stimulant.

• Subjective Effects: Produces feelings of emotional openness, euphoria, and mild stimulation. Compared to MDMA, MDEA is generally reported to be shorter-acting, somewhat milder in euphoria, and noticeably more sedating or “stoning” at higher doses.

• Pharmacokinetics:

  • Onset: ~20 to 85 minutes.

  • Duration: 3 to 5 hours.

  • Elimination Half-life: (S) MDEA ~ 4.2; (R) MDEA ~ 7.5 hours.

  • Metabolism: Hepatic, largely driven by CYP2D6 and CYP3A4 enzymes.