Acquiring verified MDMB-4en-PINACA for sale requires rigorous batch testing, validated chemical purity, and compliant laboratory distribution channels. Researchers seeking to buy MDMB-4en-PINACA online must navigate strict regulatory frameworks, verify identity using analytical spectral data, and follow standard storage protocols for synthetic cannabinoids.
Understanding the structural traits and stability parameters of MDMB-4en-PINACA ensures high-fidelity results in forensic toxicology assays, mass spectrometry reference runs, and in-vitro binding studies.
What is MDMB-4en-PINACA? (Chemical Structure & Classification)
MDMB-4en-PINACA (also known as MDMB-PENINACA or methyl (S)-3,3-dimethyl-2-(1-(pent-4-en-1-yl)-1H-indazole-3-carboxamido)butanoate) is an indazole-3-carboxamide class synthetic cannabinoid receptor agonist.
It features an indazole core with a terminal double-bond (alkene) substitution on its 5-carbon tail, distinguishing it from saturated analogs like MDMB-PINACA.
Core Technical Parameters
- Chemical Name: Methyl (2S)-3,3-dimethyl-2-[(1-pent-4-enylindazole-3-carbonyl)amino]butanoate
- CAS Registry Number: 2504100-70-1
- Molecular Formula: C20H27N3O3
- Molecular Mass: 357.45 g/mol
- IUPAC / Chemical Class: Indazole-3-carboxamide / Synthetic Cannabinoid
- Appearance: Solid powder / crystalline matrix
Receptor Binding & Pharmacodynamics
In neurochemical studies, MDMB-4en-PINACA acts as a potent, full agonist at cannabinoid CB1 and CB2 receptors.The terminal alkene modification on the pentyl chain enhances its binding efficacy compared to saturated alternatives.
[ Terminal Alkene Pentyl Tail ]
│
▼
[ Indazole Core ] ──► [ CB1 Receptor Binding Domain ] ──► [ Full Receptor Activation ]
- High CB1 Potency: Demonstrates nanomolar and sub-nanomolar binding affinity in cell-based functional assays.
- Ester Instability: The methyl ester motif renders the compound susceptible to rapid enzymatic hydrolysis during in-vitro metabolic profiling.
Sourcing Criteria & Analytical Verification
When searching for reliable suppliers offering MDMB-4en-PINACA online, institutions must prioritize laboratory-verified purity to prevent cross-contamination or erroneous chromatographic retention times.
| Analytical Metric | Target Threshold | Testing Standard |
|---|---|---|
| Assay Purity | ≥98.0% | Quantitative HPLC / GC-MS |
| Mass Identification | Base peak m/z 358 [M+H]+ | High-Resolution LC-MS |
| Spectral Verification | Conforms to reference standard | Proton NMR (1H-NMR) |
| Formulation | Neat Solid Matrix | ISO 17034 Standard |
If your institution requires certified reference standards or bulk research batches, you can order verified MDMB-4en-PINACA powder with batch-specific documentation.
Laboratory Handling & Storage Guidelines
Maintaining high compound integrity over extended research cycles requires strict adherence to climate and moisture controls:
- Storage Temperature: Keep dry solid samples stored at −20∘C in a desiccated environment to prevent ester hydrolysis.
- Solvated Aliquots: When dissolved in solvents such as Acetonitrile, Ethanol, or DMSO, store in amber glass containers purged with argon gas.
- Safety Protocols: Use chemical-resistant nitrile gloves, eye protection, and certified fume hoods to avoid accidental inhalation or direct contact.
(For complete safety handling standards, refer to your institutional containment manual).
Regulatory Status & Compliance
- United States: MDMB-4en-PINACA is controlled under Schedule I of the Controlled Substances Act.Cayman Chemical
- International Frameworks: Monitored closely under international UN drug control conventions and regional illicit drug legislation.
Disclaimer: Products listed under this description are supplied strictly for qualified academic research, forensic identification, and laboratory reference purposes. They are explicitly not intended for human or veterinary use.
Frequently Asked Questions (FAQ)
What analytical methods are best for identifying MDMB-4en-PINACA?
High-Performance Liquid Chromatography coupled with Mass Spectrometry (LC-MS/MS) and Proton Nuclear Magnetic Resonance (1H-NMR) offer definitive quantitative purity and structural confirmation.
How does MDMB-4en-PINACA differ from MDMB-PINACA?
MDMB-4en-PINACA possesses a terminal double-bond (4-pentenyl) on its tail chain, whereas MDMB-PINACA features a fully saturated pentyl tail. This structural modification significantly alters CB1 binding kinetics and receptor activation potency.
Where can I buy MDMB-4en-PINACA for laboratory research?
You can buy MDMB-4en-PINACA from certified chemical suppliers offering high-purity (≥98%) batches with third-party analytical reports.